Those patients suffering from Cirrhosis of liver experience buildup of toxins in the brain (encephalopathy) causing reduced cognitive function, full body systemic inflammation and periodontitis.
Researchers wanted to know if treating periodontitis in cirrhosis patients could reduce overall body inflammation and improve cognitive function. They created two cirrhosis patient groups suffering with mild to moderate gum disease. One group received standard periodontal disease treatment, while another group did not. Those patients who received treatment had improved cognitive function, an increase in beneficial mouth and gut bacteria and lower levels of bacteria that produce endotoxins. Researchers theorize the treated group improved because they had reduced inflammation in the mouth and lower levels of pro-inflammatory bacterial endotoxins, which reduced overall body inflammation, including inflammation in the brain (encephalopathy).
Treating periodontitis in cirrhosis patients may help improve brain function and reduce systemic body inflammation.